Transcriptomics: A method to obtain global gene regulatory mechanisms
RNA-seq processing, differential expression, and downstream pathway analysis to identify regulatory signals behind phenotypes.
Research Interest
My current research focuses on understanding and validating drug transport mechanisms by combining transcriptomics, molecular simulation, and functional assays.
I’m interested in gene regulatory mechanisms, membrane transporters, and reproducible computational workflows that connect in silico predictions to wet-lab validation.
- Bulk RNA-seq analysis, differential expression, and interpretation
- Gene regulation and network-level analysis
- Membrane protein modeling and MD simulation (GROMACS)
- Ligand transport pathways and free energy (PMF)
- Experimental validation in heterologous hosts
Research Experience
Selected projects that connect computational biology with experimental validation.
In silico validation of drug transport through MD-simulation
Membrane protein simulation workflows to evaluate ligand stability, transport pathways, and feasibility using rigorous analysis.
Functional validation of drug transport in heterologous host
Cloning, expression, and assays in a host system to test transporter function and compare against computational predictions.
